5. PDGF is overexpressed in certain cancers. This is an example of a mutation in the --- region. a. regulatory b. coding 6. DNA viruses generally cause malignancy by ----. a. inserting themselves in the host DNA, possible because their genome is șimilar to that of the host b. activating a cellular growth factor receptor, that activates the signal transduction pathway. c. inactivating a tumor suppressor gene, that results in uncontrolled proliferation.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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5. PDGF is overexpressed in certain cancers. This is an example of a mutation in the --- region.
a. regulatory
b. coding
6. DNA viruses generally cause malignancy by ----.
a. inserting themselves in the host DNA, possible because their genome is similar to that of the
host
b. activating a cellular growth factor receptor, that activates the signal transduction pathway.
c. inactivating a tumor suppressor gene, that results in uncontrolled proliferation.
7. Berkely's experiment with temperature sensitive viral mutant showed that ---
a. virus could not make the viral protein at high temperature
b. viral genome remained in the cell after the initial infection
c. continuous presence of viral protein was required to maintain the transformed malignant
phenotype of cells.
d. all of the above
e. a and b
Transcribed Image Text:5. PDGF is overexpressed in certain cancers. This is an example of a mutation in the --- region. a. regulatory b. coding 6. DNA viruses generally cause malignancy by ----. a. inserting themselves in the host DNA, possible because their genome is similar to that of the host b. activating a cellular growth factor receptor, that activates the signal transduction pathway. c. inactivating a tumor suppressor gene, that results in uncontrolled proliferation. 7. Berkely's experiment with temperature sensitive viral mutant showed that --- a. virus could not make the viral protein at high temperature b. viral genome remained in the cell after the initial infection c. continuous presence of viral protein was required to maintain the transformed malignant phenotype of cells. d. all of the above e. a and b
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