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- how can you prepare diethyl ether from an alkyl halide and any other organic or inorganic compound?Fill in the missing reagents a-e in the following scheme:The structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy. CI Pitolisant – Waxix® Below, see the synthesis of the compound. What are the reactions used? OMs OH OH CI CI O Two Williamson ether synthesis reactions. O Aminal formation followed by an ether interchange reaction. O An SN2 reaction followed by a Williamson synthesis.
- Identify the best reagents to complete the following reaction. H,Draw and Explain the reaction mechanism for the Williamson Ether reaction. Cresol is the nucleophilic component of the ether synthesis reaction and chloroacetic acid is the electrophilic component. Due to cresol being weak, a strong nucleophile has to be made before the reaction can begin. A base of KOH is added with cresol so that nucleophile can be strong before it is mixed with chloroacetic acid.OH Synthesize the compound in 2 different ways using Grignard reagents and reactions
- one hemiacetal and one acetal bond in the following dissacharide. Please them and indicate which kind of bond it is. H. Н ОН OHO HO H- H. H. H. ОН OH H. H- -H- H. H. OH ОНWhat are the hazards associated with: a) sodium methoxide and b) methanol? Draw thestep by step mechanism of reduction of a ketone using Grignard reagent.Which carbonyl is more suceptible to nucleophilic attack, carbonyl of cyclohexanone or carbonyl of hexanal? Provide two reasons