The following are sequences from three different alpha helices found in human proteins:   hBak(72-87): GQVGRQLAIIGDDINR   hCB1(196-210): VTASFTASVGSLFLT   hCB2(248-262): LVLAVLLICWFPVL   Classify each of these three helices as either a) mostly hydrophobic, b) mostly hydrophilic, or c) amphipathic. Use the helical wheel to explain your answers.   Given the character of these helices, in which part of the protein would you expect them to reside?

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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The following are sequences from three different alpha helices found in
human proteins:
 
hBak(72-87): GQVGRQLAIIGDDINR
 
hCB1(196-210): VTASFTASVGSLFLT
 
hCB2(248-262): LVLAVLLICWFPVL
 
Classify each of these three helices as either a) mostly hydrophobic, b)
mostly hydrophilic, or c) amphipathic. Use the helical wheel to explain
your answers.
 
Given the character of these helices, in which part of the protein would
you expect them to reside?
 
 
 

 

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