You are studying a novel amino acid. It has an alpha-amino and an alpha-carboxylic group, and anionizable side chain that carries a carboxylic group. A titration curve is shown below.Net chargeaCDf0 1 2 3 4 5+1 [Select]0 [Select]6 7pHChoose the letter that corresponds to the following charges on this novel acid.+2 [Select]-0.5 [ [Select]-1 [Select]8-2 [Select]I9 10 11 12 13

The titration curve of an amino acid shows the change in pH as an acid or base is added to the…

Answered: You are studying a novel amino acid. It…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Consider the second titration. 0 0 0 0 0 0 0 ☐☐☐ PH 100/ | 3 14.0 4 12.0 2 8.0 6.0 Select the pK, values of each functional group observed on the titration curve. 4.0 2.0 0.0 0.5 1.0 1.5 2.0 2.5 3.0 equivalents of [OH"] Identify which amino acid is being titrated. alanine aspartate histidine asparagine
Place each charge form of alanine under the pH condition where it would be the predominant form. The pK₁ values for the carboxyl group and amino group of alanine are approximately 2.3 and 9.7, respectively. pH 11 H | H₂C-C-COO NH₂ Does not occur in significant amounts at any pH
A peptide has the sequence Glu-His–Trp–Ser-Gly–Leu-Arg-Pro–Gly The pK, values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table. Amino acid Amino pKa Carboxyl pKa Side-chain pKa glutamate 9.60 2.34 4.25 histidine 9.17 1.82 6.00 tryptophan 9.39 2.38 serine 9.15 2.21 glycine 9.60 2.34 leucine 9.60 2.36 arginine 9.04 2.17 12.48 proline 10.96 1.99 Calculate the net charge of the molecule at pH 3. net charge at pH 3:
You have discovered a new amino acid that you name in honor of your favorite course. Twofourteeninine has an alpha-amino and an alpha-carboxylic group, and an ionizable side chain that carries an amino group. A titration curve of twofourteeninine is shown below. Net charge a P I 1 2 I 3 4 5 6 pH T 9 10 11 12 13 What are the approximate pKa values of twofourteeninine (to the nearest half-pH unit)? Check all that apply.
In the figures are the titration curves of two amino acids. Consider the first titration. 00 000 pH 10.0 4 14.0 10 9 12.0 3 نیا 8.0 Select the pK, values of each functional group observed on the titration curve. 2 9 6.0 40 20 0.0 0.5 1.0 1.5 2.0 2.5 3.0 equivalents of [CH] Identify which amino acid is being titrated. arginine asparagine histidine lysine
A peptide has the sequence Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly The pK₁ values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table. Amino acid Amino pKa Carboxyl pKa Side-chain pKa glutamate 9.60 2.34 4.25 histidine 9.17 1.82 6.00 9.39 2.38 9.15 2.21 9.60 2.34 9.60 2.36 9.04 2.17 10.96 1.99 tryptophan serine glycine leucine arginine proline Calculate the net charge of the molecule at pH 3. Calculate the net charge of the molecule at pH 8. 12.48 net charge at pH 3: net charge at pH 8:
In the space provided, draw a Haworth projection for the beta anomer of the following monosaccharide Fischer projection. CHO HO-C-H HO-C-H HO-C-H H-C-OH CH,OH
Based on the following titration table of Glycine, would you be able to recreate the same for Histidine? Glicina Increasing pH H-N-CH,-COOH -H-N-CH,-co = H-N-CH,-C00- Net charge: +1 pH COOH-pKa = 2.3 NH3-pka = 9.6 CN AEq +1 +1 2.3 (0.5°-1)+(0.5°0)=-0.5 +0.5 0.5 9.6 -1 (0.5*+1)+(0.5°0)=+0.5 -0.5 1.5 14 Given that the pKas for Histidine are the following: pka1 = 1.82 pKa2 = 9.17 pКаз %3 6.00 pL = 7.59 2.
Amino acid Cys has ionizable groups with pKa values 2.0, 8.0, and 10.0. Determine the charge on the Cys at the following pH. Be sure to write the charge in fraction with sign in front (for example, +1/2, -1/5, and +7/8). Charge when pH is at 1.0? _________ Charge when pH is at 9.0? _________ Charge when pH is at 8.0? _________ Charge when pH is at 10.0? _________
A mixture of Aspartic Acid (pl 2.98), Histidine (pl 7.59), Lysine (pl 9.74), Phenylalanine (pl 5.48) and Threonine (pl 6.53) are separated by cation exchange chromatography. What is the order of elution of these amino acids if you use gradient buffer system from pH 10 to pH 2. v First 1. Aspartic Acid v Second 2. Histidine v Third 3. Lysine 4. Phenylalanine v Fourth 5. Threonine v Fifth 6. No separation
Convert each of the following chair conformations to an open-chain from and to a Fischer projection. Namethe monosaccharides you have drawn.
Copy of The following reaction scheme shows the states of the amino acid hisitdine. Histidine has three pKa's - 2, 6 and 9.2. Which form of Histidine predominates at pH of 5? *H3N-CH-Ĉ-OH CH2 *H3N-CH-C–O- CH2 "H3N-CH-C-O- CH2 H2N-CH-C–O- CH2 +HN *HN N' -NH -NH -NH NH A C O A. A ОВ. В OC.C O D.D O E. The answer cannot be determined with information given.

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