Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 9, Problem 11TYK
Discuss Concepts Describe the possible ways in which a G-protein–coupled receptor pathway could become defective and not trigger any cellular responses.
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Draw the general structural features of a G-protein coupled receptor (GPCR)
GTP is an important high-energy molecule that facilitates the activation of many cellular sig-
nal transduction pathways. Certain genetic dysfunctions can inhibit the ability of a cell to
synthesize GTP.
Which of the following describes the most direct result of GTP synthesis inhibition?
A
B
с
D
The cell would be able to carry out reception and transduction but would not be able to
produce the cellular response in the relevant signal transduction pathway.
The G protein-coupled receptor will not be able to bind corresponding ligands, inhibiting
the reception components of the relevant signal transduction pathway.
The cell will use ATP instead of GTP to activate the G protein on the intracellular region
of the G protein-coupled receptor.
The cell would not be able to activate G proteins on the intracellular regions of G pro-
tein-coupled receptors.
. which of the following statements about heterotrimetric G proteins and their receptors is incorrect?
A: when GTP binds to the alpha subunit of the G protein, the beta-gamma subunit dissociates from the alpha subunit
B: G-protein coupled receptors contain nine transmembrane alpha helices
C: binding of arrestin causes removal of the receptor from the membrane
D: G protein- coupled receptors may be desensitized by serine phosphorylation
I had chosen option A and got it wrong. What is the Correct answer and explain how it is. Also, where did i go wrong in choosing option A?
Chapter 9 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 9.1 - What accounts for the specificity of a cellular...Ch. 9.2 - Prob. 1SBCh. 9.2 - Prob. 2SBCh. 9.3 - Prob. 1SBCh. 9.3 - Prob. 2SBCh. 9.3 - Prob. 3SBCh. 9.3 - Prob. 4SBCh. 9.3 - Prob. 5SBCh. 9.3 - Prob. 6SBCh. 9.4 - What distinguishes a steroid receptor from a...
Ch. 9.4 - By what means does a specific steroid hormone...Ch. 9.5 - Prob. 1SBCh. 9 - In signal transduction, which of the following is...Ch. 9 - Which of the following could not elicit a signal...Ch. 9 - A cell that responds to a signaling molecule is...Ch. 9 - Prob. 4TYKCh. 9 - Prob. 5TYKCh. 9 - Which of the following is incorrect about pathways...Ch. 9 - Which of the following would not inhibit signal...Ch. 9 - Prob. 8TYKCh. 9 - Prob. 9TYKCh. 9 - Prob. 10TYKCh. 9 - Discuss Concepts Describe the possible ways in...Ch. 9 - Discuss Concepts Is providing extra insulin an...Ch. 9 - Discuss Concepts There are molecules called GTP...Ch. 9 - Discuss Concepts Why do you suppose cells evolved...Ch. 9 - How would you set up an experiment to determine...Ch. 9 - Prob. 16TYKCh. 9 - Prob. 1ITDCh. 9 - Prob. 2ITDCh. 9 - Prob. 3ITD
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